Picture representing current thematic area

Projects - completed

If you have any queries or require further information regarding these R&D projects please feel free to contact Dr Jack Kay on 01932 338323 or j.kay@vmd.defra.gsi.gov.uk

Please select a year from below to see projectes completed in that year:

2013

The development of effective residue testing methods in line with national and EU statutory requirements

Project Number Project Title
VMO2169 Development of analytical methods to detect residues of active ingredients in feedingstuffs.

Development of appropriate methods to better understand the long-term health effects on man and animals coming into contact with veterinary medicines

Project Number Project Title
VMO2304 Identification of novel control methods for sheep scab mite.

Defra AMR

Project Number Project Title
OD2031 Selection of ESBL-resistance in calves feed waste milk containing antibiotic residues.
VMO2171 Trifluralin and cephalosporins in aquaculture.

2012

The development of effective residue testing methods in line with national and EU statutory requirements

Project Number Project Title
VMO2160 Contaminants in Food and Feed: Inexpensive Detection for Control of Exposure (CONffIDENCE).
VMO2173 Methods for screening and confirmatory analyses of residues of anti-fungal treatments in food animals.

Defra AMR

Project Number Project Title
OD2029 Evolution of multidrug resistance in Salmonella enterica serovar Typhimurium as a result of biocide exposure.
VMO2210 Pilot study; antimicrobial usage & antimicrobial resistance data from dairy farms with and without ESBL E. coli.

Immunological research and development

Project Number Project Title
OD2028 A generic toolbox for the molecular epidemiology of CTX-M bearing verotoxigenic E. coli and vaccine trial

2011

The development of effective residue testing methods in line with national and EU statutory requirements

Project Number Project Title
VMO2172 Extention of current analytical capbility of the UK National Surveillance Scheme to include coccidiostats not currently covered but which have EU MRLs in bovine and poultry liver
VMO2175 Extension of project VM02152 on mass spectrometry - Time of flight analytical method development.

Defra AMR

Project Number Project Title
OD2025 Antimicrobial use & carriage of antimicrobial-resistant E. coli and staphylococci in dogs and horses in the community.
VMO2211 Antibiotic Use in Food-producing animals in the UK.

Immunological Research and Development

Project Number Project Title
VM0138 The detection of anthelmintic resistance in cattle
VM0139 The efficacy of enilconazole as a treatment for Nosema infection in bees.

2010

Immunological Research and Development

Project Number Project Title
VM0135 A survey into the fate of injection site tissues in food producing animals slaughterers in the UK.
VM0133 Validation of in vitro assays to replace in vivo potency testing of rabies veterinary vaccines.

The development of effective residue testing methods in line with national and EU Statutory requirements

Project Number Project Title
VM02156 Investigation into the experimental protocols required to determine Maximum Residue Limits (MRLs) in honey: Preliminary study using organic acids as model compounds to propose ways in which withdrawal times might be calculated.
VM02164 A study of the stability of veterinary drugs in tissues during storage.
VM02165 Improve the method for detecting and determining the concentration of phenylbutazone residues in animal tissues.
VM02166 Optimisation and validation of a confirmatory method for the detection of tulathromycin in cattle and pig kidney.
VM02167 Development of a screening and confirmatory method for the detection of tilmicosin in poultry muscle and pig, cattle and sheep kidney.

The development of strategies to minimise the potential for the transfer of antimicrobial resistance from animals to humans

Project Number Project Title
VM02204 Minimising the emergence of resistance to antimicrobial drugs through rational dosage schedule design based on pharmacokinetic - pharmacodynamic (PK-PD) modelling and population PK-PD modelling.

Alternatives to Organophosphates

Project Number Project Title
OD0552 Identification of novel control methods through better understanding of the biology and physiology of the sheep scab mite.
OD0553 Investigation of the potential for the control of sheep scab using immunological approaches and the development of diagnostic tools.

Defra AMR

Project Number Project Title
OD2023 Potential risk to human and animal health from the emergence and spread of beta-lactamase resistance in animals in GB.

2009:

The development of effective residue testing methods in line with national and EU Statutory requirements

Project Number Project Title
VM02147 Preparation of animal tissues incurred with veterinary drugs.
VM02152 Rapid analysis using time of flight mass spectrometry.
VM02153 A study of natural steroid hormone levels in meat producing animals.
VM02154 Demonstration of the feasibility of novel rapid field tests for the detection of antimicrobial growth promoters in animal feed.
VM02155 Development of a method of analysis for antiviral drugs in poultry tissues.
VM02157 Development and validation of a multi-residue method for the determination of NSAIDs (including meloxicam and tolfenamic acid) in cattle, pig and horse using liquid chromatography with tandem mass spectrometry.

Development of strategies to minimise the potential for the transfer of antimicrobial resistance from animals to humans

Project Number Project Title
VM02208 Evaluating the new European broth microdilution guidelines for determining the susceptibility of C. jejuni and C. coli.
VM02209 What is the relationship between the veterinary use of antimicrobials and drug resistance in zoonotic pathogens?

Immunological Research and Development

Project Number Project Title
VM0130 Review of VMD batch release data with a view to commissioning research designed to reduce the use of animals for regulatory purposes.

2008:

The development of effective residue testing methods in line with national and EU Statutory requirements

Project Number Project Title
VM02150 Aptamers as recognition elements in trace residue analysis-rapid detection of malachite green.
VM02144 Identification of biomarkers and development of tests to detect administration of illegal and veterinary drugs in livestock.
VM02148 Screening and confirmation of triphenylmethane and phenothiazine dye residues in animal products-extension methodology.
VM02158 A literature and internet survey of medicines not authorised in the EU.
VM02159 A literature review of the occurrence, concentrations and persistence of veterinary drug residues in readily collected samples and rapid test for their detection.

Development of appropriate methods to better understand the long-term health effects on man and animals coming into contact with veterinary medicines

Project Number Project Title
VM02302 A case-control study of neuropsychological and psychiatric functioning in sheep farmers exposed to OP pesticides.
VM02115 Disabling neuropsychiatric disease in farmers exposed to organophosphates.

Development of appropriate methods to assess the potential impacts on terrestrial and aquatic environments arising from the use of veterinary medicines

Project Number Project Title
VM02504 Management of the Environmental Inputs and Risks of Cypermethrin-based Sheep Dips.

Immunological Research and Development

Project Number Project Title
VM0131 Incidence of, risk factors for, histological features of and protein expression patterns in injection site sarcomas in cats.
VM0136 Animal usage in quality control (QC) tests for the release of immunological veterinary medicinal products (IVMPs) in the UK.

2007:

The development of effective residue testing methods in line with national and EU Statutory requirements

Project Number Project Title
VM02139 Development and validation of confirmatory methodology for the determination of aminoglycoside antibiotics by LC-MS-MS.
VM02140 Investigation of the fate of veterinary drugs used in apiculture.
VM02149 Validation of analytical methods for the determination of residues of florenicol in salmon muscle and cattle kidney.
VM02151 Development of a rapid screening methodology for the detection of multiple aminoglycosides.
VM02145b Validation of an analytical method to determine residues of flunixin in bovine kidney.
VM02146c Development of screening and confirmatory methodologies for nitroxynil and oxyclozanide in bovine kidney using HPLC-MS/MS.

The development of strategies to minimise the potential for the transfer of antimicrobial resistance from animals to humans

Project Number Project Title
VM02205 Genoprofiling of multiresistant Salmonella enterica.

Development of appropriate methods to better understand the long-term health effects on man and animals coming into contact with veterinary medicines

Project Number Project Title
VM02301 Prediction of susceptibility to long-term genotoxic effects of organophosphate pesticide exposure.

Defra AMR

Project Number Project Title
OD2010 Use and abuse of non-antibiotic antimicrobials as major contributors toward the development of antimicrobial resistance.
OD2011 Development of proteomic targeted test(s) for microbial multiple antibiotic resistant zoonotic food borne pathogens.

Immunological Research and Development

Project Number Project Title
VM0132 Review of the development of alternatives and refinements to using animals in the testing of veterinary products.

2006:

The development of strategies to minimise the potential for the transfer of antimicrobial resistance from animals to humans

Project Number Project Title
VM02200 Antibiotic treatment of commercial broiler flocks: effect upon campylobacter prevalence and resistance.
VM02201 Modulation of dosing regimes to prevent development of fluoroquinolone resistance in bacteria.

Development of appropriate methods to assess the potential impacts on terrestrial and aquatic environments arising from the use of veterinary medicines

Project Number Project Title
VM02130 Evaluation of the potential risks to consumers from non-target exposure to veterinary drugs and residues indirectly entering the food chain.
VM02134 The epidemiology and control of sea lice infections in UK farmed Atlantic salmon and the role of database modelling in commercial aquaculture.
VM02502 Environmental exposure to cypermethrin released to the farmyard

Alternatives to Organophosphates

Project Number Project Title
OD0544 Immunological approaches to the control of sheep scab.
OD0545 Studies on the Biological Control of the sheep scab mite Psoroptes ovis.
OD2006 Investigation of persistence of antimicrobial resistance organisms in livestock production.

Development of appropriate methods to better understand the long-term health effects on man and animals coming into contact with veterinary medicines

Project Number Project Title
VM02300 Effects of sheep dip pesticides on differentiating nerve cells: Identification of novel markers of toxicity.
VM02126 A case-control study of neuropsychological and psychiatric functioning in sheep farmers exposed to OP pesticides.

The development of effective residue testing methods in line with national and EU Statutory requirements

Project Number Project Title
VM02125 Determination of the origin of hormones in cattle (ISOSTER).
VM02135 Detection of illegal or unauthorized hormone use (HORMONE RADAR).

Defra AMR

Project Number Project Title
VM02136 Development of rapid response gene profiling for identification of antimicrobial resistance genes in enterobacteria from food animals and humans.
OD2013 The potential for veterinary antibiotic use to cause glycopeptide resistance in human Staphylococcus aureus.



Last Updated: 24 June 2011

ISO 27001 Accredited logo Positive about disabled people logo iip logo

The VMD is an executive agency of defra defra logo